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platelet derived growth factor bb  (MedChemExpress)


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    Structured Review

    MedChemExpress platelet derived growth factor bb
    Platelet Derived Growth Factor Bb, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/platelet+derived+growth+factor+bb/PDGF-AA%2C+Rat/pm41825614-74-24-28
    Average 94 stars, based on 8 article reviews
    platelet derived growth factor bb - by Bioz Stars, 2026-10
    94/100 stars

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    Related Articles

    Over Expression:

    Article Title: PDGF-BB mitigates pericyte injury by activating the PHF19-PRC2 complex via the miR-221/BRCA1 signaling axis in Alzheimer's disease.
    Article Snippet: .. Pericytes were treated with amyloid beta peptide Aβ1–42 (SigmaAldrich) at concentrations of 5, 10, and 20 μmol/L for 24 h, followed by treatment with platelet-derived growth factor-BB (PDGF-BB; MedChemExpress, NJ, USA) at concentrations of 10, 25, 50, and 100 ng/mL for 72 h. For overexpression studies, the pcDNA3.1 vector encoding BRCA1 (pcDNA3.1-BRCA1) and miR-221/miR-222 mimics were constructed. ..

    Plasmid Preparation:

    Article Title: PDGF-BB mitigates pericyte injury by activating the PHF19-PRC2 complex via the miR-221/BRCA1 signaling axis in Alzheimer's disease.
    Article Snippet: .. Pericytes were treated with amyloid beta peptide Aβ1–42 (SigmaAldrich) at concentrations of 5, 10, and 20 μmol/L for 24 h, followed by treatment with platelet-derived growth factor-BB (PDGF-BB; MedChemExpress, NJ, USA) at concentrations of 10, 25, 50, and 100 ng/mL for 72 h. For overexpression studies, the pcDNA3.1 vector encoding BRCA1 (pcDNA3.1-BRCA1) and miR-221/miR-222 mimics were constructed. ..

    Construct:

    Article Title: PDGF-BB mitigates pericyte injury by activating the PHF19-PRC2 complex via the miR-221/BRCA1 signaling axis in Alzheimer's disease.
    Article Snippet: .. Pericytes were treated with amyloid beta peptide Aβ1–42 (SigmaAldrich) at concentrations of 5, 10, and 20 μmol/L for 24 h, followed by treatment with platelet-derived growth factor-BB (PDGF-BB; MedChemExpress, NJ, USA) at concentrations of 10, 25, 50, and 100 ng/mL for 72 h. For overexpression studies, the pcDNA3.1 vector encoding BRCA1 (pcDNA3.1-BRCA1) and miR-221/miR-222 mimics were constructed. ..

    Migration:

    Article Title: BOP1 Knockdown Attenuates Neointimal Hyperplasia by Activating p53 and Inhibiting Nascent Protein Synthesis.
    Article Snippet: .. To study the role of p53 on migration capacity change, HVSMCs were pretreated with 10μM PFT-α or DMSO followed by resuspended and cotreated with 20 ng/ml platelet-derived growth factor-BB (PDGF-BB; MedChemExpress, # HY-P7055, China). ..

    other:

    Article Title: SIRT3 mediates Tubeimoside I's inhibition on pulmonary artery smooth muscle cell proliferation and oxidative stress in pulmonary arterial hypertension.
    Article Snippet: Pulmonary arterial hypertension (PAH) is defined as a mean pulmonary arterial pressure (mPAP) ≥ 20 mmHg.. None of the approved therapies involve persistent vessel injury or vascular remodelling.. Tubeimoside I (TBM) is a triterpenoid saponin purified from the traditional Chinese medicine tubeimu.

    Concentration Assay:

    Article Title: Revolutionizing Stem Cell Therapy: A Comparative Analysis of Diverse Mesenchymal Stem Cells for Enhanced Endometrial Regeneration
    Article Snippet: .. The induction medium comprised 10% FBS, 1% penicillin G/streptomycin, transforming growth factor-β (TGF-β, HY-P7118; MCE) at a concentration of 20 ng/mL, epidermal growth factor (EGF, HYP7109; MCE) at 20 ng/mL, platelet-derived growth factor-BB (PDGF-BB, HY-P7055; MCE) at 20 ng/mL, and estradiol (E2, HY-P71085; MCE) at 10 nM. ..



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    Demonstration of the effect of aPRP or PRGF on TGF-β <t>and</t> <t>PDGF-BB</t> expression in HCs and OACs at 2 or 3 h by ELISA. (A–D) TGF-β and (E–H) PDGF-BB expressions of 2.7% aPRP, 1.8% PGRF, or 4.3% L-PRP-administered HCs and OACs are given as mean standard deviation graphs for each time point in comparison with the control groups. One-way analysis of variance (ANOVA), Tukey’s HSD post hoc test (*): p < 0.05.
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    Demonstration of the effect of aPRP or PRGF on TGF-β <t>and</t> <t>PDGF-BB</t> expression in HCs and OACs at 2 or 3 h by ELISA. (A–D) TGF-β and (E–H) PDGF-BB expressions of 2.7% aPRP, 1.8% PGRF, or 4.3% L-PRP-administered HCs and OACs are given as mean standard deviation graphs for each time point in comparison with the control groups. One-way analysis of variance (ANOVA), Tukey’s HSD post hoc test (*): p < 0.05.
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    platelet derived growth factor bb pdgf bb  (Elabscience Biotechnology)
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    Autologous blood clot characteristics and secretome comparison between healthy control ( n = 12) and metabolic syndrome/diabetic (MetS/DM) ( n = 10) participants. (A) Representative image illustrating the blood clot in culture (that was spiked in with the respective treatments prior to clot induction) and its secretome. (B) The ratio of the initial clot size (surface area) and total protein (μg/mL) released into the clot secretome within the respective treatment groups. (C–D) Quantification <t>of</t> <t>PDGF‐BB</t> (pg/mL) (C), P‐selectin (pg/mL) (D) and CCL‐5 (pg/mL) levels within the clot secretome within the respective treatment groups. Statistical analysis: Two‐way ANOVA with Sidaks multiple comparisons test. * p < 0.05, ** p < 0.01.
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    platelet derived growth factor bb  (MedChemExpress)
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    Autologous blood clot characteristics and secretome comparison between healthy control ( n = 12) and metabolic syndrome/diabetic (MetS/DM) ( n = 10) participants. (A) Representative image illustrating the blood clot in culture (that was spiked in with the respective treatments prior to clot induction) and its secretome. (B) The ratio of the initial clot size (surface area) and total protein (μg/mL) released into the clot secretome within the respective treatment groups. (C–D) Quantification <t>of</t> <t>PDGF‐BB</t> (pg/mL) (C), P‐selectin (pg/mL) (D) and CCL‐5 (pg/mL) levels within the clot secretome within the respective treatment groups. Statistical analysis: Two‐way ANOVA with Sidaks multiple comparisons test. * p < 0.05, ** p < 0.01.
    Platelet Derived Growth Factor Bb, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    platelet derived growth factor  (MedChemExpress)
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    Autologous blood clot characteristics and secretome comparison between healthy control ( n = 12) and metabolic syndrome/diabetic (MetS/DM) ( n = 10) participants. (A) Representative image illustrating the blood clot in culture (that was spiked in with the respective treatments prior to clot induction) and its secretome. (B) The ratio of the initial clot size (surface area) and total protein (μg/mL) released into the clot secretome within the respective treatment groups. (C–D) Quantification <t>of</t> <t>PDGF‐BB</t> (pg/mL) (C), P‐selectin (pg/mL) (D) and CCL‐5 (pg/mL) levels within the clot secretome within the respective treatment groups. Statistical analysis: Two‐way ANOVA with Sidaks multiple comparisons test. * p < 0.05, ** p < 0.01.
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    Autologous blood clot characteristics and secretome comparison between healthy control ( n = 12) and metabolic syndrome/diabetic (MetS/DM) ( n = 10) participants. (A) Representative image illustrating the blood clot in culture (that was spiked in with the respective treatments prior to clot induction) and its secretome. (B) The ratio of the initial clot size (surface area) and total protein (μg/mL) released into the clot secretome within the respective treatment groups. (C–D) Quantification <t>of</t> <t>PDGF‐BB</t> (pg/mL) (C), P‐selectin (pg/mL) (D) and CCL‐5 (pg/mL) levels within the clot secretome within the respective treatment groups. Statistical analysis: Two‐way ANOVA with Sidaks multiple comparisons test. * p < 0.05, ** p < 0.01.
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    Autologous blood clot characteristics and secretome comparison between healthy control ( n = 12) and metabolic syndrome/diabetic (MetS/DM) ( n = 10) participants. (A) Representative image illustrating the blood clot in culture (that was spiked in with the respective treatments prior to clot induction) and its secretome. (B) The ratio of the initial clot size (surface area) and total protein (μg/mL) released into the clot secretome within the respective treatment groups. (C–D) Quantification <t>of</t> <t>PDGF‐BB</t> (pg/mL) (C), P‐selectin (pg/mL) (D) and CCL‐5 (pg/mL) levels within the clot secretome within the respective treatment groups. Statistical analysis: Two‐way ANOVA with Sidaks multiple comparisons test. * p < 0.05, ** p < 0.01.
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    Autologous blood clot characteristics and secretome comparison between healthy control ( n = 12) and metabolic syndrome/diabetic (MetS/DM) ( n = 10) participants. (A) Representative image illustrating the blood clot in culture (that was spiked in with the respective treatments prior to clot induction) and its secretome. (B) The ratio of the initial clot size (surface area) and total protein (μg/mL) released into the clot secretome within the respective treatment groups. (C–D) Quantification <t>of</t> <t>PDGF‐BB</t> (pg/mL) (C), P‐selectin (pg/mL) (D) and CCL‐5 (pg/mL) levels within the clot secretome within the respective treatment groups. Statistical analysis: Two‐way ANOVA with Sidaks multiple comparisons test. * p < 0.05, ** p < 0.01.
    Pdgf Bb Elisa Kit, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    Demonstration of the effect of aPRP or PRGF on TGF-β and PDGF-BB expression in HCs and OACs at 2 or 3 h by ELISA. (A–D) TGF-β and (E–H) PDGF-BB expressions of 2.7% aPRP, 1.8% PGRF, or 4.3% L-PRP-administered HCs and OACs are given as mean standard deviation graphs for each time point in comparison with the control groups. One-way analysis of variance (ANOVA), Tukey’s HSD post hoc test (*): p < 0.05.

    Journal: Frontiers in Bioengineering and Biotechnology

    Article Title: Activated platelet rich plasma modulates the proliferation, apoptosis and matrix synthesis driven by growth factors in osteoarthritic chondrocytes: an in vitro study

    doi: 10.3389/fbioe.2026.1940844

    Figure Lengend Snippet: Demonstration of the effect of aPRP or PRGF on TGF-β and PDGF-BB expression in HCs and OACs at 2 or 3 h by ELISA. (A–D) TGF-β and (E–H) PDGF-BB expressions of 2.7% aPRP, 1.8% PGRF, or 4.3% L-PRP-administered HCs and OACs are given as mean standard deviation graphs for each time point in comparison with the control groups. One-way analysis of variance (ANOVA), Tukey’s HSD post hoc test (*): p < 0.05.

    Article Snippet: TGF-β1 (#E-EL-H1657, Elabscience, Wuhan, China) and PDGF-BB (#E-EL-H1577, Elabscience, Wuhan, China) levels in the cell supernatant of OACs and HCs were evaluated by ELISA.

    Techniques: Expressing, Enzyme-linked Immunosorbent Assay, Standard Deviation, Comparison, Control, Analysis

    Flow diagram illustrates the overall design and study outcomes. Activated PRP at lower EC50 promotes OAC proliferation and apoptosis and induces collagen type-II, aggrecan, TGF-β and PDGF-BB expressions in OACs. Activated PRP may improve osteoarthritic joint function. This figure was created with AI assistance under the authors’ supervision. All conceptual content and final approval were provided by the authors.

    Journal: Frontiers in Bioengineering and Biotechnology

    Article Title: Activated platelet rich plasma modulates the proliferation, apoptosis and matrix synthesis driven by growth factors in osteoarthritic chondrocytes: an in vitro study

    doi: 10.3389/fbioe.2026.1940844

    Figure Lengend Snippet: Flow diagram illustrates the overall design and study outcomes. Activated PRP at lower EC50 promotes OAC proliferation and apoptosis and induces collagen type-II, aggrecan, TGF-β and PDGF-BB expressions in OACs. Activated PRP may improve osteoarthritic joint function. This figure was created with AI assistance under the authors’ supervision. All conceptual content and final approval were provided by the authors.

    Article Snippet: TGF-β1 (#E-EL-H1657, Elabscience, Wuhan, China) and PDGF-BB (#E-EL-H1577, Elabscience, Wuhan, China) levels in the cell supernatant of OACs and HCs were evaluated by ELISA.

    Techniques:

    Autologous blood clot characteristics and secretome comparison between healthy control ( n = 12) and metabolic syndrome/diabetic (MetS/DM) ( n = 10) participants. (A) Representative image illustrating the blood clot in culture (that was spiked in with the respective treatments prior to clot induction) and its secretome. (B) The ratio of the initial clot size (surface area) and total protein (μg/mL) released into the clot secretome within the respective treatment groups. (C–D) Quantification of PDGF‐BB (pg/mL) (C), P‐selectin (pg/mL) (D) and CCL‐5 (pg/mL) levels within the clot secretome within the respective treatment groups. Statistical analysis: Two‐way ANOVA with Sidaks multiple comparisons test. * p < 0.05, ** p < 0.01.

    Journal: Wound Repair and Regeneration

    Article Title: Autologous Blood Clot Therapy for Wounds: Investigating the Chemotactic Effect on PBMCs and Fibroblasts in Diabetes

    doi: 10.1111/wrr.70153

    Figure Lengend Snippet: Autologous blood clot characteristics and secretome comparison between healthy control ( n = 12) and metabolic syndrome/diabetic (MetS/DM) ( n = 10) participants. (A) Representative image illustrating the blood clot in culture (that was spiked in with the respective treatments prior to clot induction) and its secretome. (B) The ratio of the initial clot size (surface area) and total protein (μg/mL) released into the clot secretome within the respective treatment groups. (C–D) Quantification of PDGF‐BB (pg/mL) (C), P‐selectin (pg/mL) (D) and CCL‐5 (pg/mL) levels within the clot secretome within the respective treatment groups. Statistical analysis: Two‐way ANOVA with Sidaks multiple comparisons test. * p < 0.05, ** p < 0.01.

    Article Snippet: The concentrations of platelet‐derived growth factor‐BB (PDGF‐BB) (E‐EL‐H1577, Elabscience, USA), P‐selectin (SEA569Hu; Cloud‐Clone Corp, USA) and CCL‐5 (Proteintech, USA) were determined using sandwich ELISA assays and the absorbance read at 450 nm using a microplate reader (Multiskan GO 1.00.40; Thermo‐Scientific Group, USA) according to the manufacturer's instructions.

    Techniques: Comparison, Control